Bosentan is a mixed endothelin receptor antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR.
Analysis Test
|
Specification |
Result |
|
|
Description |
white crystalline powder |
Conforms |
|
Solubility |
Easily soluble in water, unsoluble in ethanol |
Conforms |
|
PH |
6.0 to 7.5 |
6.9 |
|
Solution clarity and color |
solution should be clear and colorless |
Conforms |
|
Related substances |
5CMP 0.3% |
0.01% |
|
Chloride |
0.05% |
Conforms |
|
Ammonium |
0.05% |
Conforms |
|
Fe |
0.01% |
Conforms |
|
Phosphate |
0.1% |
Conforms |
|
Loss on drying |
6.0% |
1.3% |
|
Heavy metals |
0.002% |
Conforms |
|
Arsenide |
0.0001% |
Conforms |
|
Bacterial Endotoxins |
0.3EU/mg |
Conforms |
|
Microbial Limit |
Conforms |
Conforms |
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