Amiloride HCl

Product Description

potassium-sparing diuretic, used in the management of hypertension andcongestive heart failure. Amiloride was also tested as treatment ofcystic fibrosis.

Mechanism of Action:

Amiloride works by directly blocking the epithelial sodium channel(ENaC) thereby inhibiting sodium reabsorption in the late distal convoluted tubules, connecting tubules, and collecting ducts in thekidneys (this mechanism is the same for triamterene).This promotes the loss of sodium and water from the body, but without depletingpotassium. The drug is often used in conjunction with thiazide (e.g.co-amilozide) or loop diuretics (e.g. co-amilofruse). Due to its potassium-sparing capacities, hyperkalemia (high blood potassium levels) is occasionally observed in patients taking amiloride. The risk is high in concurrent use of ACE inhibitors or spironolactone.

Reliable Medical Grade Quality

Our Amiloride HCl complies with the highest medicine-grade specifications, ensuring a consistent and high-purity product. Designed for pharmaceutical applications, the powder form allows for versatility in formulation while its extended 5-year shelf life enhances handling convenience for distributors and manufacturers alike.


Therapeutic Applications and Benefits

Amiloride HCl is widely utilized in the treatment and management of hypertension and congestive heart failure. Its efficacy in maintaining electrolyte balance without significant potassium loss adds clinical value, making it a recommended option by healthcare professionals. The high purity ensures optimal therapeutic outcomes.